Hello !

I’m Georgia Kefala

I’m currently looking for a PhD in Biophysics starting in 2023

About Me

How I became passionate about Biophysics

My interest in biophysics is rooted in the desire to apply the theories and methods of physics to understand how biological systems work. Through my different research projects, I have become fascinated studying the mechanics of how the molecules of life are made, how different parts of a cell move and function, how complex systems in our bodies — the brain, the circulation, the immune system, etc. — work.

I’m particularly interested in the research field of cell mechanics. What is appealing to me is the complexity of cells, the out-of-the-box thinking required to develop methods and accelerate progress in this field using the quantitative sciences of physics, mathematics, and chemistry. I’m aware that cell mechanics is a field where perseverance, dedication and passion are vital to succeed, and I’m certain I possess those skills.

Working in Biophysics also gives me the unique opportunity to work alongside scientists from many fields such as mathematics, chemistry, physics, engineering, pharmacology, materials sciences, etc. who all use their skills to explore and develop new tools for understanding how all life works.


Master of Science, Research in Physics: Biological Physics and Soft Matter Specialization (120 ECs)

Leiden University
Sept 2021 – Present
Leiden, The Netherlands

Average of 8.4/10 on the first year
Two research projects:

  • Thesis 1: Using soft hydrogel micro-particles for stress measurements in hetero-spheroids

  • Thesis 2 to be defined during my 2nd internship on February 2023

Modules: Biophysics, Soft Matter Physics, Statistical Physics, Quantum Mechanics, Origins and Evolution of Life, Engineering of Living Systems, Mechanical Metamaterials

Bachelor of Science in Physics (4-year degree / 240 ECTS)

Aristotle University of Thessaloniki, Greece
Sept 2017 – June 2021
Thessaloniki, Greece

Graduated with a grade of 8.48/10

  • Thesis: Improving ranking after protein-protein docking simulations using Dipole Moment, Rg and pKa

Modules: Physics, Mathematics, Programming, Physics Laboratories, Biophyics

EMBL Lautenschläger Summer School: Talents teach talents Visualising Life – Interdisciplinary Approaches to Biology

European Molecular Biology Laboratory
July 2019
Heidelberg, Germany

  • Granted full Scholarship by the Laboratory

  • Attended lectures on Imaging Biology, Microscopy, Developmental and Cell Biology, Morphogenesis and Machine Learning

  • Built a confocal microscope, imaged living organisms, performed image analysis using python

Work Experience

High School

Research project (MSc thesis)

Leiden Institute of Physics (LION), Leiden University

August 2022 – Present

Leiden, The Netherlands

Title: Using soft hydrogel micro-particles for stress measurements in hetero-spheroids | Supervisor: Thomas Schmidt, Prof.

Studying the stress fibroblasts and melanoma cells apply, by looking at the deformations in hydrogel micro-particles serving as stress sensors

  • Lab experience: cell culture, spheroid development, cell labelling, fluorescence microscopy, development of hydrogel micro-particles, labelling and activating the stress sensors (hydrogel micro-particles)

  • Developing a computational method in MATLAB to distinguish the two cell types and measuring the stress with methods in python and MATLAB

High School

Summer internship

Department of Biochemistry and Biotechnology, University of Thessaly, Greece

July 2021 – October 2021

Thessaly, Greece

Title: In vitro chondrogenesis induction by short peptides of the carboxy-terminal domain of Transforming Growth Factor β1| Supervisor: G. E. Papadopoulos, Ass. Prof.

  • Submitted for publication in Science Reports, Nature

  • Collected and analyzed data, comparing the possible structures of protein-peptide docking (by calculating the pKa)

High School

Research project (BSc Thesis)

Department of Physics, Aristotle University of Thessaloniki, Greece

October 2020 – June 2021

Thessaloniki, Greece

Title: Improving ranking after protein-protein docking using Dipole Moment, Rg and pKa | Supervisors: N. Frangis, G. E. Papadopoulos

  • Automated using python, tcl and bush the calculation of dipole moment, Rg and pKa for 10 protein complexes

  • Analyzed the data from 4000 possible structures, developing a method to identify the best structure


NWO Biophysics

October 2022
Veldhoven, The Netherlands

  • Presented a poster of the MSc thesis research project

Nanotexnology, International Conferences and Exhibition on Nanotechnologies – Organic Electronics and Nanomedicine

Laboratory for Thin Films – Nanobiomaterials – Nanosystems – Nanometrology
July 2021
Thessaloniki, Greece July 2021

  • Presented a poster of the BSc thesis research project

  • Supported the organization of the event (reception duties, assisted presenters and attendees with the online environment)

Other Experiences

High School

Member of the Education Committee of the MSc program

Department of Physics, Leiden University

November 2021 – November 2022

Leiden, The Netherlands

  • Advised the committee and provided feedback on possible solutions to student issues, collected student concerns

High School

Teaching Assistant, Physics Department

Aristotle University of Thessaloniki

Feb 2019 – Jan 2021

Thessaloniki, Greece

  • Courses : Electricity-Magnetism (Physics III) and Astronomy & Astrophysics (20 hours of workload per week)

High School


October 2019 – Sept 2020

Thessaloniki, Greece

  • Tutored 2 students on their third year of their bachelor, in Mathematics, Physics and Programming

High School

Cashier, Barista and Waitress

Rithymna (café)

Feb 2022 – Present

Leiden, The Netherlands

  • Assisted the owner with all the shop’s tasks on the weekends


My education and different work experiences allowed me to develop the skills necessary to pursue a PhD in Biophysics

Hard Skills

Python 70%
C 40%
Mathematica 40%
OriginLab 60%
Excel 90%
TCL 60%

Current Research

Poster presented in NWO Biophysics 10/10/2022

Contact Me

Georgia Kefala


Email: georgiamk864@gmail.com

Phone number: +30 69 47 63 88 24